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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLAT
All Species:
33.64
Human Site:
S475
Identified Species:
46.25
UniProt:
P10515
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10515
NP_001922.2
647
68997
S475
L
E
G
R
S
K
I
S
V
N
D
F
I
I
K
Chimpanzee
Pan troglodytes
XP_522180
647
68973
S475
L
E
G
R
S
K
I
S
V
N
D
F
I
I
K
Rhesus Macaque
Macaca mulatta
XP_001107013
647
68918
S475
L
E
G
R
S
K
I
S
V
N
D
F
I
I
K
Dog
Lupus familis
XP_546524
647
68802
S475
L
E
G
R
S
K
I
S
V
N
D
F
I
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF4
642
67923
S470
L
E
G
K
G
K
I
S
V
N
D
F
I
I
K
Rat
Rattus norvegicus
P08461
632
67147
S460
L
E
G
K
G
K
I
S
V
N
D
F
I
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509202
536
56600
S373
N
D
F
I
I
K
A
S
A
L
A
C
L
K
V
Chicken
Gallus gallus
XP_417933
681
72018
S509
V
S
D
N
V
K
L
S
V
N
D
F
I
I
K
Frog
Xenopus laevis
NP_001082239
628
66845
S456
K
A
D
N
I
K
L
S
F
N
D
F
I
I
K
Zebra Danio
Brachydanio rerio
NP_997832
652
69250
S480
K
A
E
N
I
K
L
S
V
N
D
F
I
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609118
512
54233
A351
I
I
K
A
V
A
I
A
S
L
K
V
P
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
L346
F
I
I
K
A
S
A
L
A
C
Q
R
V
P
E
Sea Urchin
Strong. purpuratus
XP_001190217
487
52117
S326
V
I
K
A
A
A
L
S
C
Q
K
I
P
D
A
Poplar Tree
Populus trichocarpa
XP_002303212
512
55370
A351
V
I
K
A
A
A
L
A
L
R
K
V
P
Q
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
A378
V
V
K
A
A
A
L
A
L
R
K
V
P
Q
C
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
R321
A
I
T
V
A
A
K
R
V
P
D
A
N
A
Y
Red Bread Mold
Neurospora crassa
P20285
458
48601
R297
A
M
G
I
A
S
K
R
V
P
T
V
N
S
S
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.4
N.A.
85.6
85.1
N.A.
70.3
72
72.8
71.9
N.A.
42
N.A.
41.7
39.8
Protein Similarity:
100
99.2
98.6
92.8
N.A.
90.2
89.6
N.A.
74.5
78.4
82.6
78.9
N.A.
53.9
N.A.
55
54.1
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
13.3
60
53.3
60
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
73.3
60
66.6
N.A.
20
N.A.
26.6
26.6
Percent
Protein Identity:
36.3
N.A.
N.A.
38.6
33.5
36.6
Protein Similarity:
50.2
N.A.
N.A.
53
48.2
48.8
P-Site Identity:
0
N.A.
N.A.
0
13.3
13.3
P-Site Similarity:
33.3
N.A.
N.A.
33.3
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
24
36
30
12
18
12
0
6
6
0
6
12
% A
% Cys:
0
0
0
0
0
0
0
0
6
6
0
6
0
0
12
% C
% Asp:
0
6
12
0
0
0
0
0
0
0
59
0
0
6
0
% D
% Glu:
0
36
6
0
0
0
0
0
0
0
0
0
0
6
6
% E
% Phe:
6
0
6
0
0
0
0
0
6
0
0
53
0
0
0
% F
% Gly:
0
0
42
0
12
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
30
6
12
18
0
42
0
0
0
0
6
53
53
0
% I
% Lys:
12
0
24
18
0
59
12
0
0
0
24
0
0
6
53
% K
% Leu:
36
0
0
0
0
0
36
6
12
12
0
0
6
0
0
% L
% Met:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
18
0
0
0
0
0
53
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
0
24
6
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
6
6
0
0
12
0
% Q
% Arg:
0
0
0
24
0
0
0
12
0
12
0
6
0
0
0
% R
% Ser:
0
6
0
0
24
12
0
65
6
0
0
0
0
6
6
% S
% Thr:
0
0
6
0
0
0
0
0
0
0
6
0
0
0
0
% T
% Val:
24
6
0
6
12
0
0
0
59
0
0
24
6
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _